Tuesday, May 10, 2011

Day 2 - OIT Peanut Clinical Trial

Day two began at 8 am again.  This one seemed like a breeze!  We came in and did vitals, then got our first dose in applesauce.  It was such a tiny amount after yesterday!!  The goal for today was to get him to the first dose level.  The total dose for today was SO much smaller than what we did yesterday, so no one expected him to even blink at these doses...and he didn't.  He went through just fine.  We did the next dose every 30 minutes until he made it to the maximum dose for the day and then we waited 2 hours to make sure there was no reaction.  So, that is where we will start out our dosing.  Tomorrow we will go in for our first official dose.  Over the course of the next 10 - 12 months, we will go back every two weeks to get a new dose.  They will do bloodwork every 3 months or so and skin tests once a year.  After we reach the maximum dose, then we get to do the maintenance dose until his peanut IgE drops below 2...then we food challenge again!  If he passes the food challenge, then we go a month with nothing...no dose, no exposure...then we food challenge again.  If he passes that, then we "open challenge"...which means he eats something made with peanuts....like a cookie or something.  That is a ways away and in the meantime, he will get a daily dose of peanut.  It sounds crazy, but it seems to be working for a number of kids and adults to help them lose their allergies.
So...more to come...much more!  :)

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